Clinical Significance of Changes of Interleukin-15 Levels in Children with Kawasaki Disease
- VernacularTitle:川崎病患儿白细胞介素-15水平变化的临床意义
- Author:
yi, CHEN
;
tong-xin, CHEN
;
ya-zhong, ZHU
;
rong-fa, WANG
- Publication Type:Journal Article
- Keywords:
interleukin-15;
mucocutaneous lymph node syndrome;
child
- From:Journal of Applied Clinical Pediatrics
2004;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the role of interleukin-15(Il-15)in pathogenesis of Kawasaki disease(KD)and its potential cli-nical value.Methods Thirty patients with KD were selected in Xinhua hospital from Oct.2004 to Jan.2006.The serum concentration of IL-15 was measured by enzyme linked immunosorbent assay(ELISA)in acute stage and convalescent stage of KD,and 30 children with low respiratory inflection and 20 healthy children were studied as controls.Results Serum IL-15 level in acute KD was significantly higher than that in normal control,and the two sides were remarkably different in statistics(q=25.64 P