Comparison of Preventive Effect of Maternal-Infant Hepatitis B Virus Vertical Transmission by Symphysial Immunoprophylaxis
- VernacularTitle:联合免疫措施阻断乙型肝炎母婴传播的疗效比较
- Author:
jie, GU
;
yi-lu, WANG
;
lin, ZHAO
- Publication Type:Journal Article
- Keywords:
hepatitis B;
hepatitis B immunoglobulin;
disease transmission,vertical;
hepatitis B virus DNA
- From:Journal of Applied Clinical Pediatrics
2004;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy by inoculated with hepatitis B immunoglobulin(HBIG) and hepatitis B vaccine in dif-ferent doses and time points to prevent maternal-infant vertical transmission of hepatitis B virus(HBV).Methods Gravidas positive for HBV were selected and measured HBV DNA,according to difference HBV DNA degrees divided into A,B,C groups.Every group was randomly divided into 4 groups using a variety of combined immunity methods to compare its efficacies.Results There were no significant differences in the positive rate of HBV and HBsAb in A,B groups by statistics analysis.There were significant differences in the positive rate of HBV and HBsAb in group C by statistics analysis.Conclusion According to the different HBV DNA take different combined immunodeficiency approach to prevent maternal-infant vertical transmission.
