Intervention Effects of Granisetron Hydrochloride on Vasovagal Syncope in Rabbits
- VernacularTitle:盐酸格拉司琼对兔血管迷走性晕厥的干预作用
- Author:
yan, DONG
;
hong-wei, WANG
;
ping, HUANG
;
pei-xuan, CHENG
;
zhi, XIA
;
liang-pin, ZHANG
- Publication Type:Journal Article
- Keywords:
granisetron hydrochloride;
syncope,vasovagal;
intervention
- From:Journal of Applied Clinical Pediatrics
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of granisetron hydrochloride on vasovagal syncope(VVS) in rabbits.Methods Twenty-four healthy New Zealand rabbits were divided stochastically into control group and intervention group,12 in each group. The control group was injected intravenously with normal saline. The intervention group was injected intravenously with granisetron hydrchloiride.Rabbit VVS models were established,each was taken at 4 points in time in the bloodletting process:T1,T2,T3,T4,to compare the bloodletting time,the concentration of 5-hydroxytryptamine(5-HT) in T2,T3,T4 and the total blood volume between the groups,and monitor the heart rate, blood pressure during the entire process.Results 1.The time of intervention group in T2,T3,T4 was longer than the time of control group obviously(P
