Collection of Peripheral Blood Stem Cells from Low-Weight Infants with Osteopetrosis and Its Clinical Signi-ficance
- VernacularTitle:低体质量石骨症患儿外周血干细胞采集及其临床意义
- Author:
xiang-feng, TANG
;
zuo, LUAN
;
nan-hai, WU
;
you-zhang, HUANG
;
su-qing, QU
;
xiao-hong, HU
;
xiao-jun, GONG
;
wei-peng, LIU
- Publication Type:Journal Article
- Keywords:
peripheral blood stem cells;
collection;
osteopetrosis;
low-weight;
child
- From:Journal of Applied Clinical Pediatrics
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the safety of collection of peripheral blood stem cells(PBSCs) from low-weight infants with osteopetrosis(OP) and its clinical significance. Methods One case of low-weight infants with OP received PBSCs collection using a continuous-flow blood cell separator,and the safety of collection process was observed.The amount of monocyte cell(MNC) and CD34+ cell were noted and its clinical significance was analyzed.Results Low-weight infants with OP could tolerate collection process,the number of collection MNC and CD34+ cells were 10.06?108/kg,2.74?106/kg.Conclusion Adequate PBSCs can be collected from OP who need not be mobilized,thus can offer backup for graft failure.PBSCs collection from low-weight infants is safe.
