Significance of Serum Cardiac Troponin I and Creatine Phosphokinase-Isoenzyme-MB in Asphyxia Neonate
- VernacularTitle:窒息新生儿血清肌钙蛋白I和磷酸肌酸激酶同工酶变化的意义
- Author:
xin-chao, YU
;
hui, WANG
;
li-jin, WANG
- Publication Type:Journal Article
- Keywords:
cardiac troponin I;
myocardial injury;
asphyxia;
infant,newborn;
creatine phosphokinase-isoenzyme-MB
- From:Journal of Applied Clinical Pediatrics
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of cardiac troponin I (cTnI) and creatine phosphokinase-isoenzyme-MB (CK-MB) on early diagnosis of heart damage in asphyxia neonate.Methods A total of 47 cases of asphyxia neonates were divided into mild-asphyxia group( n=29 ) and severe-asphyxia group(n=18),and the levels of cTnI and CK-MB were quantitatively determinated by ELISA and enzyme kinetics, respectively.Results After birth for the first day, the serum levels of cTnI and enzymatic activities of CK-MB were all significantly higher in mild-asphyxia group[(2.25?0.54)?g/L,(223.4?23.5)U/L]and severe-asphyxia group[(4.25?0.83)?g/L,(256.3?21.8) U/L)]than those in control group(P_a0.05), however the results in severe-asphyxia group[(1.54?0.72)?g/L,(188.9?21.5)U/L]were significantly higher than those in control group (P_a
