Significance of Changes of Serum Endotheline,D-Dimer and Fibrinogen in Infants with Pneumonia Complicated with Heart Failure
- VernacularTitle:肺炎并心力衰竭患儿内皮素、D-二聚体、纤维蛋白原变化的意义
- Author:
run-ying, LI
;
jun-ling, ZHU
;
li-hua, WANG
;
bao-yuan, XU
;
xiao-ling, ZHENG
- Publication Type:Journal Article
- Keywords:
pneumonia;
heart failure,congestive;
endotheline;
D-dimer;
fibrinogen;
child
- From:Journal of Applied Clinical Pediatrics
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the changes of serum endotheline(ET),D-dimer and fibrinogen(Fbg) in infants with pneumonia complicated with heart failure(HF) and explore the changes of blood coagulation,fibrinolysis,and endothelial cell function.Methods Eighty patients with infant pneumonia complicated with HF and 20 controls were studied.Serum ET,D-dimer,Fbg,activated partial thromboplastin time(APTT),prothrombin time(PT) and thrombin time(TT) were measured.Results ET,D-dimer,Fbg,APTT in every group had differences.With the disease deteriorating,the values of ET,D-dimer,Fbg increased,but the values of APTT decresed gradually.There were positive relations between ET and D-dimer(r=0.42 P