Leves of Tumor Necrosis Factor Alpha,Interleukin-1 Beta,Interleukin-6 in Serum and Cerebrospinal Fluid in Children with Intracranial Infection
- VernacularTitle:颅内感染患儿血清及脑脊液肿瘤坏死因子-?、白细胞介素-1?、白细胞介素-6水平变化的意义
- Author:
fa-guang, MU
;
ying, OU-YANG
;
chang-hui, CHEN
;
jian-bo, ZHANG
- Publication Type:Journal Article
- Keywords:
central nervous system infections;
tumor necrosis factor;
interleukin-1;
interleukin-6
- From:Journal of Applied Clinical Pediatrics
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the fuction of tumor necrosis factor alpha(TNF-?),interleukin-1 beta(IL-1?) and interleukin-6(IL-6) in children with intracranial infection.Methods TNF-?,IL-1? and IL-6 levels of serum and cerebrospinal fluid(CSF) were determined in the purulent meningitis group(25 cases),tuberculous meningitis group(17 cases),viral meningitis group(30 cases)and control group(20 cases)by enzyme-linked immunosorbent assay(ELISA).Results The levels of TNF-?,IL-1? and IL-6 obviously increased in CSF compared with that in the serum (Pa