Curative Effect of Low Melocular Heparin on Hypercoagulability of Kawasaki Disease
- VernacularTitle:低分子肝素治疗川崎病患儿高凝状态的疗效
- Author:
xiao-qing, LI
;
nan, ZHOU
;
yang, SONG
;
de-cheng, SU
- Publication Type:Journal Article
- Keywords:
low melocular weight heparin;
mucocutaneoas lymph node syndrome;
hypercoagulability;
curative effect
- From:Journal of Applied Clinical Pediatrics
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the curative effect of low melocular weight heparin(LMWH) on the hypercoagulability in acute Kawasaki disease(KD).Methods Forty-six patients were diagnosed KD.Twenty-two cases out of all KD patients whose serum concentration of whether platelet(PLT) or fibrinogen(FIB) was significantly increased or who were found thrombus in their coronary artery by ultrasonic Doppler were treated with LMWH by subcutaneous injection once every day for 7-10 days.All the patients were divided into 2 groups accor-ding to whether using LMWH or not:H group(using LMWH) and NH group(no using LMWH).It were detected before and after treatment that included thrombin time(TT),activated partial thromboplastin time(APTT),international normalized ratio(INR),FIB,plasma mucosity,erythrocyte sedimentation rate(ESR),hematocrit(HCT) and situation of haemorrhage.Results 1.Before treatment,PLT and FIB of patients in H group were significantly higher than those in NH group(Pa
