Curative Effect of Prostaglandin E_1 in Treating Neonates with Complete Transposition of Great Arteries
- VernacularTitle:前列腺素E_1治疗新生儿完全性大动脉转位的疗效
- Author:
bo, YU
;
zhen-lang, LI
;
sha-sha, LI
;
zi-ying, ZHANG
- Publication Type:Journal Article
- Keywords:
alprostadil;
prostaglandin E1;
transposition of the great arteries;
infant,newborn
- From:Journal of Applied Clinical Pediatrics
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the curative effect of prostaglandin E1(PGE1)on maintaining Sa(O2) and life span in the neonates with complete transposition of the large arteries(TGA).Methods Eleven of 19 neonates complete TGA received continuous PGE1 with the dosage of 5-20 ng/(kg?min),while the other 8 cases were set as control.The body temperature,Sa(O2),heart rate and blood pressure of both groups were recorded during the trial.Results The average Sa(O2) in trial group was (82.3?3.56)%,which had significant difference compared with the control group(t=8.232 P=0.001).The life span in trial group was much longer than control group.The body temperature,heart rate and blood pressure of trial group had no significant fluctuations.Conclusion PGE1 has an compkete effect on maintaining the ope-ning of patent ductus arteriosus (PDA) in TGA patients,which can improve the Sa(O2) and prolong the life span.
