Value of Brain Natriurectic Peptide and Cardiac Troponin I in Diagnosis and Prognosis on Heart Failure in Children
- VernacularTitle:脑钠素与肌钙蛋白I在小儿心力衰竭诊断、预后评估中的意义
- Author:
hui, LIU
;
ke-sheng, XIN
- Publication Type:Journal Article
- Keywords:
heart failure;
brain natriurectic peptide;
cardiac troponin I;
diagnosis;
prognosis
- From:Journal of Applied Clinical Pediatrics
2006;0(24):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore diagnosis and prognosis of heart failure in children by measuring brain natriurettic peptide(BNP) and cardiac troponin I(CTnI).Methods Forty-one children subjects with heart failure were chosen,and then they were divided into three stages,early stage of heart failure,stage of heart failure and stage of recovery according to the ROSS cardiac function score method.In contrast with the former group,41 healthy children were chosen as control group.BNP and CTnI levels of blood plasma were analyzed by radioimmunoassay(RIA) and chemiluminescent immunoassay(CLIA) respectively,the relationship between the BNP level of blood plasma and prognosis of CHF group was analyzed.Results At early stage of heart failure,BNP and CTnI levels began to rise.They amount to highest peaks at stage of heart failure and went down at stage of recovery.But they were still higher than those of control group(P
