Clinical Analysis of 7 Children with Fatal Virus Encephalopathy
- VernacularTitle:儿童致死性病毒性脑病7例
- Author:
shi-jun, HE
;
chang-chong, LI
- Publication Type:Journal Article
- Keywords:
encephalopathy,virus,fatal;
hepatic dysfunction;
convulsion
- From:Journal of Applied Clinical Pediatrics
2006;0(22):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore clinic manifestations and laboratory investgation of virus encephalopathy.Methods The clinical course,cerebrospinal fluid(CSF),hepatic dysfunction,computerized tomography of 7 cases treated in our hospital from October 1999 to March 2005 were retrospectively reviewed.Results Seven cases of virus encephalopathy were typically associated with a suddent onset of high fever,severe convulsion,rapidly progressive coma,marked elevations of alanine aminotransferase(AST) and aspartate transaminase(ALT).Four cases died,3 cases had severe sequelae.Blood ammonemia was normal,brain CT scans revealed peripheral or basal nuclei low-density areas.Conclusion Children with a sudden onset of high fever,severe convulsions,rapidly progressive coma may have a poor prognosis.