Clinical Significance of Measuring Interleukin-13 in Serum and Pulmonary Function in Infants with Bronchiolitis
- VernacularTitle:毛细支气管炎患儿血清白细胞介素-13及肺功能检测的意义
- Author:
yue, LI
;
zhen-ze, CUI
;
yan, HUANG
- Publication Type:Journal Article
- Keywords:
child;
bronchiolitis;
interleukin-13;
respiratory function tests
- From:Journal of Applied Clinical Pediatrics
2006;0(22):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical significance of measuring IL-13 in serum and dynamics of pulmonary function in infants with bronchiolitis.Methods A total of 50 infants with bronchiolitis(30 in acute phase,20 in recovery phase) and 20 infants in healthy controls were recruited into this study.IL-13 level in serum were detected with Sandwich enzyme linked immunosorbent assay(ELISA),at the same time the object′s respiratory function were tested,then the above indexes were compared.Results The level of serum IL-13 in recovery phase of bronchiolitis was significantly lower than that in acute phase of bronchiolitis and those of both 2 groups were significantly higher than that in control group(all P0.05).Conclusions IL-13 plays a role in pathogenesis in infants with bronchiolitis.The reduction of level of IL-13 will contribute to recovery of infants with bronchiolitis.During the acute phase of bronchiolitis higher resistance can be seen.
