Changes of Intercellular Adhesion Molecule-1 in Pathogenesis of Children with Mycoplasm Pneumoniae Pneumonia
- VernacularTitle:肺炎支原体肺炎患儿可溶性细胞间黏附分子-1的变化
- Author:
yi, XIN
;
hong-mei, MA
;
wei-na, SONG
;
chang-yun, LIU
- Publication Type:Journal Article
- Keywords:
mycoplasm pneumoniae pneumonia;
asthma;
soluble intercellular adhesion molecule-1;
child
- From:Journal of Applied Clinical Pediatrics
2006;0(22):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the levels of soluble intercellular adhesion molecule-1(SICAM-1) in serum and induced sputum in children with mycoplasma pneumoniae pneumonia(MPP),and to investigate the role of SICAM-1 in pathogenesis of MPP.Methods The levels of SICAM-1 in serum and induced sputum and sputum cell count were measured by enzyme linked immunosorbent assay(ELISA) kit in 44/34 children with MPP in acute episode period,36/28 children in remission episode period and 38/30 healthy children.Results The levels of serum SICAM-1,sputum SICAM-1 and percent of neutrophil(N),lymphocyte(L),eosinophile(EO),mast cell(Ma) were significantly higher in acute episode period in MPP than those in remission episode period and control group,respectively((all P0.05);)the indexs in remission period and in controls showed no marked difference.The le-(vels of) serum and sputum(SICAM-1) in children with asthma attack in acute and remission episode periods in MPP increased significantly compared with those in children without asthma in both periods(P
