Correlation between Serum Interleukin -4,12 and Cellular Immunity in Children with Asthma
- VernacularTitle:哮喘患儿血清白细胞介素-4、12与细胞免疫的相关性
- Author:
Ai-hua, CUI
;
Yi-zhen, FENG
;
Xiao-jing, SUN
;
Jun, LIANG
;
Ming-xia, ZHANG
- Publication Type:Journal Article
- Keywords:
asthma;
child;
interleukin-12;
interleukin-4;
T cell subgroup;
immunity
- From:Journal of Applied Clinical Pediatrics
2006;0(16):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the changes of serum interleukin(IL)-4,IL-12 and correlation with cellular immunity in children with asthma of different stages.Methods Fifty asthmatic children were randomly selected, including 30 cases in attack stage (group A) and 20 cases in remission stage (group R). At the same time, 22 healthy children were studied as normal controls (group N).The levels of IL-12 and IL-4 ,T cells subgroups and erythrocyte immunity were detected.Results 1.Serum IL-12 levels were (24.44? 13.26 ),(42.30?12.65),(44.68?28.28) ng/L in group A, R and N,respectively. There was significant difference in three groups (F=8.92 P
