Changes of Epithelial Cell Derived Neutrophil-Activating Protein 78 in Synovial Fluid and Serum in Children with Rheumatoid Arthritis
- VernacularTitle:类风湿性关节炎患儿关节滑液和外周血上皮嗜中性粒细胞激活肽水平变化
- Author:
xiao-yu, WU
;
zhan-ju, LIU
;
zhong-sheng, DONG
- Publication Type:Journal Article
- Keywords:
child;
arthritis,juvenile rheumatoid;
synovial fluid;
enzyme linked immunosorbent assay
- From:Journal of Applied Clinical Pediatrics
2006;0(21):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the concentration of epithelial cell derived neutrophil-activating protein 78(CXCL-5) in the sy-(novial) fluid(SF) and peripheral blood in children with rheumatoid arthritis(RA) and evaluate its clinical relevance to the disease development.Methods SF and peripheral sera were taken from 26 children with RA and 16 healthy controls,and CXCL-5 was measured by enzyme linked immunosorbent assay(ELISA).CXCL-5 in SF was also measured in RA children after receiving steroid treatment.Results The levels of CXCL-5 was significantly higher than that in the SF of RA children compared with healthy controls(P0.05).Interestingly,CXCL-5 markedly decreased in RA children after steroid treatment(P
