High-Dose Methotrexate in Treatment of Acute Lymphoblastic Leukemia
- VernacularTitle:大剂量甲氨蝶呤治疗急性淋巴细胞白血病
- Author:
li-hua, WANG
;
bao-yuan, XU
;
jun-ling, ZHU
;
hai-hua, ZHOU
- Publication Type:Journal Article
- Keywords:
high dose-methotrexate;
acute lymphoblastic leukemia;
treatment
- From:Journal of Applied Clinical Pediatrics
2006;0(21):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05) in incidence rate for bone marrow suppression,gastrointestinal reaction,hepatic damage and mucosa damage and infection between different therapic courses.Central nervous system leukemia(CNSL) occured in one high risk case followed up at 12 month after complete remission(CR);the incidence rate was 12.5%.Conclusions HD-MTX is practicable in basic-level hospitals,as long as there are perfect preparation,fitness hydration and alkalization and leucovorin rescue being used in time.
