Relationship between Helicobacter Pylori Infection and Henoch-Schonlein Purpura in Children
- VernacularTitle:幽门螺杆菌感染与儿童过敏性紫癜的关系
- Author:
hui, LI
;
fu-yue, DING
;
ling, LIU
;
qiong, XU
- Publication Type:Journal Article
- Keywords:
child;
Henoch-Schonlein purpura;
helicobacter pylori
- From:Journal of Applied Clinical Pediatrics
2006;0(20):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between helicobacter pylori(Hp) infection and Henoch-Schonlein purpura(HSP) in children and find out the etiological treatment for HSP.Methods Positive rate of Hp-IgG between normal children and children with HSP were compared.Infection of Hp was detected by rapid urease test,and relationship between infection of Hp and clinical symptom in Henoch purpura was analyzed.Children with HSP were randomly divided into two groups and were respectively treated with Hp eradication therapy together with conventional therapy and conventional therapy only.The recurrence rates were compared.Results The infection rate in 150 children with HSP,especially the 90 children with Henoch purpura was significantly higher than that in normal children,and it was in positive correlation with abdominal symptom.Hp infection with triplex therapy for 2 weeks in HSP could reduce the recurrence of HSP.Conclusions Hp infection may be one of the reasons of HSP in children,and is related with Henoch purpura.Eradication of Hp can reduce recurrence of HSP.
