Intrauterine Growth Retardation Models Caused by Maternal Food Restriction and Its Effect on Important Organs
- VernacularTitle:食物限制法建立宫内发育迟缓模型及对其重要器官的影响
- Author:
hui-ming, YANG
;
meng, MAO
;
su-fei, YANG
;
fan, YANG
;
tao, YU
- Publication Type:Journal Article
- Keywords:
food restriction;
intrauterine growth retardation;
rat
- From:Journal of Applied Clinical Pediatrics
2006;0(19):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effects of different maternal rats food restriction on newborn rats.Methods Pregnant rats were randomly divided into 4 groups:3 model groups and control group.The model groups were given middling food restriction throughout pregnancy,severe food restriction from pregnant day 14,severe food restriction from pregnant day 7,respectively.Effects of maternal rats food restriction on newborn rats in growth,main organs weight,and small for gestational age(SGA) occurrence were compared.And his-(tiocyte) morphology of cerebra and stomach were observed.Results The weight,height,trail length,and weight of cerebra,heart,lung,(liver),stomach,spleen,and kidney of newborn rats in model groups were significantly different from those in control group(all P