Changes of Interleukin-18 and Lymphocyte CD_(54) in Children with Congestive Heart Failure
- VernacularTitle:充血性心力衰竭患儿血清白细胞介素-18和淋巴细胞CD_(54)变化
- Author:
gui-qin, DUAN
;
shui-ying, ZHAO
;
jin-dou, AN
- Publication Type:Journal Article
- Keywords:
interleukin-18;
intercellular adhesion molecule-1;
heart failure,congestive;
cytokines;
flow cytometry
- From:Journal of Applied Clinical Pediatrics
2006;0(18):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discover the role of interleukin-18(IL-18) and CD_(54) in congestive heart failure(CHF),and evaluate the diagnostic value of IL-18 and CD_(54) in CHF.Methods Blood samples were collected from 52 children with CHF,included 18 cases in classⅡ,17 cases in class Ⅲand 17 cases in class Ⅳ.Fifteen healthy children were normal control group.The levels of IL-18 was(detec-)ted by ELISA method and the expression of CD_(54) was examined by flow cytometry.Results The levels of IL-18 and CD_(54) in CHF were significantly higher than those of control subjects(P0.05),but the levels were respectively significantly higher than that of control subjects(P
