Mutability Ultra Sodium Pyrosulfite Intake Spermatogonium on Ultrastructure Changes in Mice Testis
- VernacularTitle:超量焦亚硫酸钠摄入后雄性小鼠睾丸超微结构变化及其对精原细胞的致突性
- Author:
quan-xiang, MA
;
ze-shan, MAO
;
jin-zhu, HAN
;
xiang-shan, YUAN
- Publication Type:Journal Article
- Keywords:
ultra sodium pyrosulfite;
spermatogonium;
sister-chromosome exchanges;
mutability;
ultrastructure
- From:Journal of Applied Clinical Pediatrics
2006;0(18):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the mutability of ultra sodium pyrosulfite intake on ultrastructure changes and spermatogonium mice testis.Methods Forty male Kunming mice were used.Experimental group had been exposed to ultra sodium pyrosulfite by fed for 10 days,and sodium pyrosulfite′s contaminated dose were 1% and 1‰.Mice were killed at 11~(th) day,and ultrastructure changes were observed under transmission electron microscopy(TEM) and the tests of sister chromosome exchanges(SCE) were made.Mmutation of ultra sodium pyrosulfite on spermatogonium of mice testis was judged.Results Compared with control group,there was a significant increase of SCE ratio in spermatogonium of testis in experimental groups(P
