Clinical Study on Large Dose Intravenous Immunoglobulin in Decreasing Incidence of Asthma Following Bronchiolitis
- VernacularTitle:大剂量静脉丙种球蛋白防治毛细支气管炎发展为哮喘的临床研究
- Author:
hong, LI
;
ya-ting, WANG
- Publication Type:Journal Article
- Keywords:
bronchiolitis;
asthma;
intravenous immunoglobulin
- From:Journal of Applied Clinical Pediatrics
2006;0(18):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the efficiency of large dose intravenous immunoglobulin(IVIG) in decreasing incidence of asthma following bronchiolitis.Methods One hundred and sixty-eight children with bronchiolitis were chosen to use different treatment plans,81 children receiving large dose of IVIG[ 0.4 g/(kg?d)] daily,on the basis of routine treatment for 5 days,while other 87 children were reserved as control group receiving routine treatment only,which were followed up 5 to 10 years.Results After following up 5 to 10 years,only 17 cases in 81 patients with bronchiolitis receiving large dose IVIG developed into asthma.However,46 cases in control group developed into asthma.The incidence of asthma was 20.99% and(52.87%) in two groups,respectively,showing significant(differe-)nce between them(P
