Expression of Induced Nitric Oxide Synthase and Its Significance of Rats′ Kidney after Ischemia-Reperfusion
- VernacularTitle:缺血再灌注大鼠肾脏诱导型一氧化氮合酶表达的意义
- Author:
pu, ZHAO
;
ling-di, SUN
- Publication Type:Journal Article
- Keywords:
nitric oxide synthase;
immunohistochemical method;
ischemia/reperfusion
- From:Journal of Applied Clinical Pediatrics
2006;0(17):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression levels and the roles of induced nitric oxide synthase(iNOS) in rats′ kidney after interruption of blood flow and the following ischemia-reperfusion(IR)injury.Methods Rats were divided into 3 groups:interruptions(5,15,30 min),IR(2,5,8,24,48,72 h),control groups.They were killed at different time points.Kidney tissue samples were studied by immunohistochemical method.Results iNOS increased significantly(P