Serum Levels of Helper T Cell 1/Helper T Cell 2 Cytokines in Children with Hepatitis B Virus-Associated Glomerulonephritis and Its Clinical Significance
- VernacularTitle:乙型肝炎病毒相关性肾炎患儿血清辅助性T细胞1/辅助性T细胞2细胞因子水平及其临床意义
- Author:
rui-xia, LIN
;
qing, YANG
;
min-guang, CHEN
- Publication Type:Journal Article
- Keywords:
hepatitis,B virus-associated glomerulonephritis;
cytokines;
child
- From:Journal of Applied Clinical Pediatrics
2006;0(17):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the significance of helper T cell 1(Th1)/Th2 cytokines unbalance in children with hepatitis B virus-associated glomerulonephritis(HBV-GN).Methods The serum levels of interferon-gamma(IFN-?),interleukin-2(IL-2) and IL-4 were determined in 22 children with HBV-GN and 18 children with HBV by enzyme-linked immunosorbent assay(ELISA),respectively,and the difference of Th1/Th2 cytokines in the 2 groups.Results Serum levels of IL-2 and IFN-? in children with HBV-GN were decreased(P
