Treating Persistent Henoch-Schonlein Purpura Nephritis by Injecting Methylprednisolone into Intra-Renal Capsule in Children
- VernacularTitle:肾囊内注射甲泼尼龙治疗儿童难治性紫癜性肾炎
- Author:
zhi-hui, LI
;
jin-hua, HE
;
yan, YIN
;
cui-rong, DUAN
- Publication Type:Journal Article
- Keywords:
Henoch-Schonlein purpura nephritis,persistent;
intra-renal injection therapy;
methylprednisolone;
child
- From:Journal of Applied Clinical Pediatrics
2006;0(17):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the results of treating the persistent Henoch-Schonlein purpura nephritis(HSPN) by injecting methylprednisolone into intra-renal capsule in children.Methods Twenty-two patients(aged from 6 to 13 years) with persistent HSPN were randomly divided into 3 groups.Group I was treated with prednisone;group Ⅱ was treated with high dosage methylprednisolone by venous injection,while group Ⅲ was treated by injecting methylprednisolone into intra-renal capsule.The 24 h urinary protein excretion,the levels of serum albumin and creatinine,or the blood cholesterole in children with persistent HSPN were detected at the beginning,4 weeks and 8 weeks of the study.The blood pressure,body weight were detected in the study duration.Results The values of 24 h urinary protein excretion were(2.35?1.09),(0.97?0.37),and(0.99?0.52) g(P
