Significance of Expression of Nerve Growth Factor and Slouble Fas in Children with Viral Myocarditis
- VernacularTitle:神经生长因子、可溶性Fas在病毒性心肌炎中的表达意义
- Author:
rong, JIAO
;
xing-yuan, HUANG
;
ying, CHEN
;
gen-rong, MAI
- Publication Type:Journal Article
- Keywords:
viral myocarditis;
nerve growth factor;
slouble Fas;
child
- From:Journal of Applied Clinical Pediatrics
2006;0(13):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of nerve growth factor(NGF) and slouble Fas(sFas) in children with viral myocarditis(VM),and the relationship with immunity,with the aim to provide evidence and basis for the diagnosis and treatment of VM.Methods The serum levels of NGF and sFas were detected by two-site enzyme-linked immunosorbent assy(ELISA) in 43 children with VM,and 20 normal heathy children as controls.Results The serum levels of both NGF and sFas in children with the acute stage(course in less than month and 1-2 months)and the procrastinate and chronic stages of VM were significantly higher than those of healthy children(P0.05).Conclusion The increased serum expression levels of NGF and sFas are related to the process of viral myocarditis,which confirms the relationship between the onset of VM and immune factors.
