Correlative Study on Sera and Induced Sputum Clara Cell Secretory Protein Levels in Children with Asthma
- VernacularTitle:哮喘儿童血清、诱导痰Clara细胞分泌蛋白的相关研究
- Author:
zhi-hong, WEN
;
sheng-zhou, NONG
;
qing-ling, XIE
;
hua, DU
;
fang, CHEN
;
qiong-yan, HU
;
wei-ya, ZHOU
- Publication Type:Journal Article
- Keywords:
Clara cell secretory protein;
sera;
induced sputum;
asthma;
child
- From:Journal of Applied Clinical Pediatrics
2006;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the role of Clara cell secretory protein(CCSP) in asthmatic children and compare the levels of CCSP in sera and induced sputum.Methods Thirty-four children with asthma who were in remission and 25 healthy controls were enrolled.Sera and hypertonic saline-induced sputum were obtained in asthmatic children,and sera alone were obtained in control subjects.The le-(vels) of CCSP were measured in sera and induced sputum by enzyme linked immunosorbent assay.Results Asthmatic children,compared with controls,had significantly lower concentration of CCSP in sera(P
