Changes of S-100B Protein in Umbilical Cord Blood of Asphyxial Neonates with Hypoxic-Ischemic Encephalopathy and Its Clinical Significance
- VernacularTitle:窒息后缺氧缺血性脑病新生儿脐血S-100B蛋白变化的意义
- Author:
huai-yan, WANG
;
xi-rong, GUO
- Publication Type:Journal Article
- Keywords:
infant,newborn;
hypoxic-ischemic,brain;
umbilical cord blood;
S-100B protein
- From:Journal of Applied Clinical Pediatrics
2006;0(14):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study clinical significance of S-100B protein in umbilical cord blood of asphyxial neonates with hypoxic-ischemic encephalopathy(HIE).Methods Forty-three cases of healthy infants were regarded as control group(group 1).Sixty cases of asphyxial neonates were divided into two groups(44 cases without HIE as group 2;another 16 cases with HIE as group 3).S-100B protein levels in umbilical cord blood of three groups were measured with enzyme-linked immunosorbent assay retrospectively. Results Levels of S-100B protein in group 1,group 2 and group 3 were(1.055?0.356) ?g/L,(1.572?0.533) ?g/L and(2.394?(0.943) ?g/L,) respectively.S-100B protein levels in umbilical cord blood of group 2 and group 3 were significantly higher than that of group 1(t=2.306,7.991 P
