Expression of Heme Oxygenase-1 and Its Significance of Rat Kidney after Ischemia-Reperfusion
- VernacularTitle:血红素氧合酶-1在缺血再灌注大鼠肾脏的表达及意义
- Author:
pu, ZHAO
;
ling-di, SUN
;
hong-yan, ZHANG
- Publication Type:Journal Article
- Keywords:
heme oxygenase-1;
immunohistochemistry;
ischemia-reperfusion
- From:Journal of Applied Clinical Pediatrics
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression levels and the roles of heme oxygenase-1(HO-1) in rat kidney after interruption of blood flow and the following ischemia-reperfusion(IR)injury.Methods Rats were divided into 3 groups: interruptions(5,15,30 min),IR group(2,5,8,24,48,72 h),and control group.They were killed at different time points.Kidney tissue samples were studied by immuneohistochemical method.Results The expressions of HO-1 raised significantly in both ischemia group of 30 min((P
