Changes of Interleukin-6 in Serum and Urine in Children with Primary Nephrotic Syndrome and Their Clinical Significance
- VernacularTitle:原发性肾病综合征患儿足量激素治疗前后血、尿白细胞介素-6检测的意义
- Author:
yong-wen, YU
;
qiang-ying, ZHANG
- Publication Type:Journal Article
- Keywords:
nephrotic syndrome;
interleukin-6;
child
- From:Journal of Applied Clinical Pediatrics
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical significance of the changes of interleukin-6(IL-6) contents in serum and urine in children with primary nephrotic syndrome(PNS).Methods The contents of IL-6 in serum and urine in 38 cases of PNS were exa-(mined) by ELISA before and after treatment with prednisone 2 mg/(kg?d) for 8 weeks.Results Before the treatment with prednisone,the contents of IL-6 in serum in steroid-responsive group and steroid-resistant group were significantly higher than those in the normal controls(P0.05).In the steroid-responsive group and steroid-resistant group,the levels of IL-6 in urine were significantly higher than those in the normal controls(P0.05).The contents of IL-6 in steroid-resistant group in serum and urine had significant difference in the comparison with the normal controls(P
