Study on Serum Leptin,Insulin Like Growth Factor-1,Interleukin-6 and Tumor Necrosis Factor-Alpha Levels of Newborn Infants with Hypoxic-Ischemic Encephalopathy
- VernacularTitle:缺氧缺血性脑病新生儿血清瘦素、胰岛素样生长因子-1、白细胞介素-6和肿瘤坏死因子-?水平的变化
- Author:
fang, GONG
;
yong-rong, ZOU
;
cheng-lin, WANG
;
hu-ming, ZHANG
;
zhao-min, HUANG
;
ze-kai, YANG
- Publication Type:Journal Article
- Keywords:
infant,newborn;
hypoxi?-ischemia,brain;
Leptin;
insulin like growth factor-1;
interleukin-6;
tumor necrosis factor-alpha
- From:Journal of Applied Clinical Pediatrics
2004;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine levels of serum Leptin,insulin like growth factor-1(IGF-1),interleukin-6(IL-6) and tumor necrosis factor-alpha(TNF-?) in newborn infants with hypoxic-ischemic encephalopathy(HIE).Methods The asphyxiated and normal term neonates were included.The HIE group contained 45 cases and control group 20 cases.Serum Leptin,IGF-1,IL-6 and TNF-? levels were measured by a sensitive enzyme-linked immunosorbent assay.Results In asphyxiated term neonates,serum Leptin,IGF-1,IL-6 and TNF-? levels were significantly higher or lower than those in control group(all P
