Changes and Significances of Serum Leptin and Interleukin-1? before and after Treatment with Risperidone in Children with Schizophrenics
- VernacularTitle:精神分裂症患儿利司培酮治疗前后血清瘦素和白细胞介素-1?变化的意义
- Author:
xue-qin, SONG
;
jing-ping, ZHAO
;
lu-xian, LV
- Publication Type:Journal Article
- Keywords:
schizophrenia;
leptin;
interleukin-1;
risperidone
- From:Journal of Applied Clinical Pediatrics
2004;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes and significances of serum leptin and interleukin-1?(IL-1?)before and after treatment with risperidone in children with schizophrenics.Methods Thirty-one cases with first-episode children with schizophrenia were chosen in patient group.Their body weight and height were measured before and 8 weeks after treatment with risperidone to calculate the body mass index(BMI),and their fasting serum leptin and IL-1? were assayed radio-immunity method.Thirty-one healthy controls were measured at the same time.Results BMI and the level of serum leptin in patients of post-treatment increased significantly compared with those of pre-treatment(all P
