Significance of Serum Interleukin-6 in Attack or Stable Stage of Asthmatic Children
- VernacularTitle:不同时期哮喘患儿血清白细胞介素-6变化的意义
- Author:
zhi-hong, WEN
;
mei, HONG
;
yan-ling, TAO
;
qiong-yan, HU
;
li-hua, SU
- Publication Type:Journal Article
- Keywords:
children;
asthma;
interleukin-6
- From:Journal of Applied Clinical Pediatrics
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the role and clinical significance of interleukin-6(IL-6) in children with bronchial asthma.Methods Sera were collected from 29 cases with asthmatic attacks,32 asthmatic children who in stable conditions,and 20 health children.Serum IL-6 concentrations were measured by radioimmunoassay(RIA).Results 1.Asthmatic children appeared significantly higher levels of serum IL-6 during asthmatic attacks as compared to those in stable conditions and healthy ones respectively(P3 years old had significantly higher serum IL6 concentrations than ≤3 years old children in remission.Conclusion IL-6 may participate pathogenesis of asthma,and it may play different biological roles during asthmatic attacksas or stable conditions.
