Study on T-Cell and T-Helper Cell Subpopulation Function in Children with Recurrent Tonsillitis in Remission Period
- VernacularTitle:反复扁桃体炎患儿缓解期T细胞亚群及辅助性T淋巴细胞亚群的功能状态
- Author:
yong, YANG
;
zong-bo, CHEN
- Publication Type:Journal Article
- Keywords:
tonsillitis;
children;
T-cell subpopulation
- From:Journal of Applied Clinical Pediatrics
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the state of T-cell and T-helper cell subpopulation in children with recurrent tonsillitis(RT) in remission period and make clear its role on pathogenesis in children with RT.Methods The expression of membrane molecule on T-cell subsets was analyzed in 27 RT children and 21 control health children by using immunofluorescence and flowcytometry,the levels of interferon-?(IFN-?) and interleukin-4(IL-4) in culture supernatant of peripheral blood mononuclear cells(PBMC) were detected by enzyme linked immunoadsorbent assay(ELISA).Results The CD4~+ and CD3~+ cell were significantly lower in RT children than those of the controls(P0.05),a ratio of CD4~+/CD8~+ was disproportion(P0.05),the ratio of Th1/Th2 was disproportion(P
