Cyclosporin A Combination with Angiotensin-Converting Enzyme Inhibitor in Treatment of Alport′s Syndrome
- VernacularTitle:环孢素和血管紧张素转化酶抑制剂干预治疗Alport′s综合征
- Author:
bing, LIU
;
wei-xun, HE
;
guang-hua, ZHU
;
ming-jun, FANG
- Publication Type:Journal Article
- Keywords:
Alport′s syndrome;
cyclosporin A;
angiotensin-converting enzyme inhibitor
- From:Journal of Applied Clinical Pediatrics
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the possibility of medication treatment in Alport′s syndrome(AS).Methods Two boys with AS,received cyclosporin A(CyA) in combination with angiotensin-converting enzyme inhibitor(ACEI) or only ACEI,which lasted 22 months and 20 months,respectively.Results After the treatments with the medication,there was obvious effectiveness in the 2 patients with relieved symptom and almost normal serum standard,especially the permanent and obvious recession of proteinuria.There was no side effects of medication during the treatment.Conclusion Patients with AS can be treated with CyA and ACEI,with symptomatic recession,as well as suspend the progression of pathology of kidney.
