Induction of Apoptosis and Upregulation of Fas Ligand and Fas-Associated Death Domain by Doxorubicin in Human Jurkat Leukemia T-Cells
- VernacularTitle:阿霉素诱导Jurkat白血病细胞凋亡及上调Fas配体和Fas相关死亡域(英文)
- Author:
jia-hao, LIU
;
hong-li, TANG
;
wei-yong, RUAN
;
wei, WANG
;
li, HUANG
- Publication Type:Journal Article
- Keywords:
leukemia;
apoptosis;
flow cytometry;
Western blot;
FasL;
Fas-associated death domain;
caspase
- From:Journal of Applied Clinical Pediatrics
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05) at 6 hour;at 12 hour,only the highest dose,1 mg/L,significantly induced cell apoptosis;while the lowest dose,0.1 mg/L,did not significantly caused cell apoptosis for all time points.After exposure to the doses of 0.2 and 0.5 mg/L for 24 or 36 hours,a significant increase in percentage of apoptotic cells was observed(P
