Clinical Significance of Detection of Serum Interleukin-8 in Children with Thyroid Disfunction
- VernacularTitle:甲状腺功能异常患儿血清白细胞介素-8检测的意义
- Author:
ping, MIAO
;
han-hua, LIN
;
zhi, XIA
- Publication Type:Journal Article
- Keywords:
interleukin-8;
hyperthyroidism;
hypothyroidism;
children
- From:Journal of Applied Clinical Pediatrics
2004;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of serum interleukin 8(IL-8) level in children with thyroid disfunction and its clinical significance in children with autoimmune thyroid disease(AITD).Method Serum IL-8 of 30 children with hyperthyroidism,16 children with hypotyroidism and 20 health children were detected by double antibody enzyme linked immunossorbent assay(ELISA).Results Serum IL-8 levels in hyperthyroidism and hypothyroidism children were significantly higher than that in controls(P0.05).With the remission of the diseases, IL-8 levels decreased; there was a significant difference between serum IL-8 levels in patients before and after therapy (P
