Dynamic Change of Cerebral Blood Flow of Newborns with Hypoxic-Ischemic Encephalopathy
- VernacularTitle:缺氧缺血性脑病新生儿脑血流动力学的动态变化
- Author:
shi-qing, SHAO
;
dong-mei, NING
;
shu-fang, JIN
- Publication Type:Journal Article
- Keywords:
infant,newborn;
hypoxic-ischemic encephalopathy;
cerebral blood flow;
hemodynamic
- From:Journal of Applied Clinical Pediatrics
2004;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the dynamic change of cerebral blood flow of newborns with hypoxic-ischemic encephalopathy(HIE).Methods Cerebral blood flow of middle cerebral artery and pulsatility index(PI) on 75 newborns with HIE and 50 normal infants were examined with transcranial doppler sonography at different time points,and the relations between cerebral blood flow and clinic indexes were analyzed.Results The blood velocity of normal infants increased gradually, and PI decreased from 2 to 5 days.The velocities were lower than that of normal infants,and PI was higher at 12th hour and 1st day, but during 2-5 days,the velocities got higher and PI got lower, in which the decrease of velocities correlated positively with Apgar scores and the increase of velocities were negatively correlative to Apgar scores.Compared with the neonates who had poor prognosis retrospectively with those had good prognosis, the velocity changes were found to be more significant.Conclusion The change of cerebral blood flow can show the pathophysiology of HIE and prognosticate the prognosis of neonates with HIE.
