Value of Nuclear Factor-?B for Early Diagnosis on Neonatal Sepsis
- VernacularTitle:核因子-?B对新生儿败血症的早期诊断价值
- Author:
qian, NI
;
ding, XU
;
yi, CUI
- Publication Type:Journal Article
- Keywords:
infant,newborn;
neonatal sepsis;
nuclear factor-?B;
flow cytometry
- From:Journal of Applied Clinical Pediatrics
2004;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression and the effect of nuclear factor-?B(NF-?B) in neonatal sepsis.Methods We separated 77 newborn infants into 3 groups, which were septic group (26 cases),non-septic group (31 cases) and control group (20 cases). NF-?B existed in PBMC was detected in 3 different periods, including at admission, after the 24th hour and 48th hour of admission, of the septic group and the non-septic group by flow cytometry. At the same time, the sample of the septic group and the non-septic group were drawn for blood cultures at admission before using antibiotics.Results The expression of NF-?B in septic group was more significant than that in the other 2 groups (P
