Changes of Serum Vascular Endothelial Growth Factor in Children with Henoch - Schonlein Purpura
- VernacularTitle:过敏性紫癜患儿血管内皮生长因子变化的意义
- Author:
qiang, WANG
;
wei, DONG
- Publication Type:Journal Article
- Keywords:
vascular endothelial growth factor;
Henoch-Schonlein purpura;
children
- From:Journal of Applied Clinical Pediatrics
2004;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of serum vascular endothelial growth factor (VEGF) and its effects on pathoge nesis in children with Henoch - Schonlein purpura(HSP). Methods Serum VEGF was detected by sandwich ELISA in 20 children with HSP in acute phase and 15 children in remission phase and 16 normal children. Results The serum VEGF levels in children with HSP in acute phase(533.85? 127.63) ng/L were significantly higher than those in remission phase (160.47 ? 37.39) ng/L and normal control (68. 93 ? 19. 16) ng/L. One - way analysis of variance between them was significant difference ( F = 158. 86 P