Immune Responses of Th1/Th2 in Children with Mycoplasma Pneumoniae Pneumonia
- VernacularTitle:肺炎支原体肺炎患儿Th1/Th2免疫应答的状况
- Author:
jian-min, CAI
;
zhen-hai, WANG
;
hong-lie, ZHOU
;
tang-xin, CHEN
- Publication Type:Journal Article
- Keywords:
children imycoplasma pneumoniae;
Th1 cells;
Th2 cells;
interferon- ?;
interleukin-4
- From:Journal of Applied Clinical Pediatrics
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the immune responses of Th1 and Th2 subsets of T cells in 26 children with mycoplasma pneumo-niae pneumonia(MPP).Methods ELISA was used to detect the levels of interferon- ?( IFN- ?) and interleukin-4(IL-4) in the serum in 12 healthy children as normal controls and 26 patients of acute stage as acute stage MPP group, 9 of whom in recovery stage were as recovery stage MPP group. Results IFN - ? level in acute stage MPP group was significant higher than that in normal controls (P 0.05); and IFN - 7/IL - 4 ratio was significant higher than that in normal controls( P0.05).Conclusion Thl responses increase and Th2 responses decrease in children with MPP,and this kind of response persists during the recovery stage.
