Significance of Detection of Chemokines in Serum of Infants Respiratory Syncytial Virus Infection
- VernacularTitle:呼吸道合胞病毒感染患儿血清趋化因子测定的意义
- Author:
sheng-ying, XIA
;
dong-chi, ZHAO
;
dian-ding, ZOU
- Publication Type:Journal Article
- Keywords:
respiratory syncytial virus;
macrophage inflammatory protein-1?;
regulated upon activation normal T cell expressed and secreted
- From:Journal of Applied Clinical Pediatrics
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the roles of macrophage inflammatory protein- 1?(MIP- 1?) and regulated upon activation normal I" cell expressed and secreted(RANTES)in pathogenesis of respiratory syncytiai virus(RSV) infection,and explore the roles of these chemokines asthma caused by RSV mfectron. Methods Serum samples were obtained from 45 infants with RSV infection, including 10 hroivhial asthma, 15 bronchitis or pneumonia ,20 upper respiratory tract infection ;20 healthy infants with non - RSV infection as the normal group. ELISA method was used to determine the concentrations of MIP- 1? and RANTES in serum. Results MIP - 1? and RANTES levels in infants with RSV infection were much higher than those of non - RSV infected healthy subjects (P
