Clinical Significance of P- Selectin Expression in Children with Viral Encephalitis
- VernacularTitle:P-选择素在病毒性脑炎患儿中表达的临床意义
- Author:
hua, CHENG
;
bao-qiang, YUAN
;
chun-ping, XU
;
ming, LU
- Publication Type:Journal Article
- Keywords:
viral encephalitis;
P- selection;
flow cytometric;
cerebral infarction
- From:Journal of Applied Clinical Pediatrics
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical significance of P - selection expression in children with viral encephalitis and the correlation between this expression and the cerebral infarction with critical viral encephalitis. Methods Flow cytometric was employed to detect the expression of P- selection on the surface of platelet membrane in 44 children with viral encephalitis(20 light patients and 24 critical patients) and 20 healthy control children. The area of the cerebral infarction was determined by computed tomographic scan in 20 patients with critical viral encephalitis. The correlation between the two variables was analyzed. Results The expressions of P - selection on the surface of platelet membrane on less than 5 days and on 2 weeks after the onset of viral encephalitis were significantly higher in critical patients than those in normal control children and light patients( P
