Changes Hydrogen Sulfide in Plasma of Children with Congenital Heart Disease
- VernacularTitle:先天性心脏病患儿血浆硫化氢变化的意义
- Author:
yu-wen, SU
;
ya-guang, DING
;
chun-yu, ZHANG
;
qing-you, ZHANG
;
jian-guang, QI
;
chao-shu, TANG
;
jun-bao, DU
- Publication Type:Journal Article
- Keywords:
hydrogen sulfide;
congenital heart disease;
pulmonary hypertension
- From:Journal of Applied Clinical Pediatrics
2004;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of hydrogen sulfide (H_2S) level in plasma in order to explore the role of H_2S in the development of pulmonary hypertension (PH) secondary to congenital heart disease (CHD).Methods There were 9 CHD patients and 9 normal children in this study. The plasma concentration of H_2S and pulmonary artery pressure (PAP) of each child were measured. Meanwhile, the relationship between H_2S level and PAP was analyzed.Results The plasma level of H_2S in the group of CHD significantly decreased compared with control group (32.13?2.25) ?mol/L vs [(43.69?2.05)?mol/L, P
