Relationship between Vascular Endothelial Growth Factor and Pool Prognosis in Nephroblastoma
- VernacularTitle:血管内皮生长因子与肾母细胞瘤不良预后的关系
- Author:
qing-jiang, CHEN
;
qian, ZHANG
;
yan, SHAN
- Publication Type:Journal Article
- Keywords:
nephroblastoma;
vascular endothelial growth factor;
immuneohistochemical
- From:Journal of Applied Clinical Pediatrics
2004;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the connection between vascular endothelial growth factor(VEGF) and pool prognosis in nephroblastoma.Methods Serum VEGF was measured with immuneohistochemical(ELISA) methods in 35 children of nephroblastoma at preope-ration,1 week,2 weeks after surgery respectively. Simple visiting happened after surgery 4,8,16,32 weeks.The countrol group was 35 healthy children. Result Before surgery,the median VEGF in the children was (89.47?22.45) ?g/L.After surgery 1 week,2 weeks,levels in the children fell significantly to (2.75?0.31) ?g/L,(1.52?0.18) ?g/L.There was a significant difference compared with preoperation ( t =4.125 P