Changes of Pancreatic Islets Functions and Insulin Resistance Index in Children with Severe Stress
- VernacularTitle:应激状态下危重症患儿胰岛功能及胰岛素抵抗指数的变化
- Author:
shi-ning, NI
;
ying-xia, GU
;
qian-qi, LIU
;
jia-chang, XU
;
pei-rang, ZHANG
- Publication Type:Journal Article
- Keywords:
risky sign of disease;
pancreatic islets function;
insulin resistance index
- From:Journal of Applied Clinical Pediatrics
1992;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the saccharometabolism with the pancreatic islets functions and insulin resistance index in children with severe stress. Methods Thirty children with severe stress and 30 healthy children in control group were tested. The levels of fasting blood glucose (FBG), fasting insulin (FINS) and fasting C - peptide (FCP) were detected by radioimmunoassay respectively and insulin sensitivity index (ISI), insulin resistance index (IR) and fasting blood cell function index (FBCI) were calculated statistically. Results There were significant differences between the children with severe stress and the normal controls in the levels of FINS, FCP and FBG,(all P0.05). Conclusion There is insulin resistance with the significant decrease in the insulin sensitivity index and significant increase in insulin resistance index in the children with severe stress, which may cause the disorder in glucose metabolism in children with severe stress.
