Influence of Thyroid Status on Serum Levels of Leptin and Leptin mRNA in Rats
- VernacularTitle:甲状腺激素对大鼠血清瘦素及其mRNA水平的影响
- Author:
fang, YU
;
han-hua, LIN
- Publication Type:Journal Article
- Keywords:
thyroid;
function;
thyroid hormones;
leptin
- From:Journal of Applied Clinical Pediatrics
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influence of thyroid status on serum level of leptin and expression of leptin mRNA in rats with hypothyroidism or hyperthyroidism.Methods Fifty rats were artificially rendered hyperthyroidism and hypothyroidism by L-thyroxine or methimazole and divided into 5 groups.The serum of T 3,T 4,TSH,leptin concentration and expression of leptin mRNA were measured in 5 groups.Results Serum leptin concentration was significantly correlated with weight of rats in 5 groups(P
