Action of Erythrocytes Immuno - Adhering in Pathogenesis of Children with Mesangio - Proliferative Glomeru-lonephritis
- VernacularTitle:红细胞免疫黏附功能在系膜增生性肾小球肾炎发病机制中的作用
- Author:
lan, GU
;
jin - jin, JIANG
;
yuan, SU
;
li, WU
;
wei-xun, HE
- Publication Type:Journal Article
- Keywords:
mesangioproliferative glomerulonephritis;
erythrocytes;
leukocytes;
immunoadhering functions
- From:Journal of Applied Clinical Pediatrics
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the role of erythrocytes immunoadhering in the pathogenesis of the patients with mesangiopro-liferative glomerulonephntis (MsPGN). Methods The immunoadhering functions of erythroeytes and leukoeytcs were measured in 31 patients with no- IgAN,24 patients with IgAN and 30 normal children by rosette tests:RCR,RICR,TRR,TNR and TLR. Results 1. The immunoadhering functions of erythroeytes (RCR and TRR) of the patients with no- IgAN and IgAN were obviously decreased compared to those of control group,but RICR showed no significant difference;2. The immunoadhering functions of leukocytes (TNR and TLR ) of the patients with no- IgAN and IgAN were obviously decreased compared to those of control group;3 The degree of the decreased immunoadhering functions of erythroeytes was correlated respectively with that of the immunoadhering functions of leukoeytes. Conclusions The decrease of the function of erythroeyte and leukocyte immunoadhering plays an important role in the pathogenesis in patients with MsPGN. These rosette tests may be used in clinic.
