Pathogenic Effect of Platelet Derived Growth Factor in Henoch - Schonlein Purpura Nephritis and Influence of Heparin
- VernacularTitle:紫癜性肾炎患儿血小板源生长因子的意义及肝素对其影响
- Author:
huijuan, ZHU
;
yuhang, JIANG
;
yibing, , WANG
- Publication Type:Journal Article
- Keywords:
platelet derived growth factor;
Henoch - Schonlein purpura nephritis;
Heparin
- From:Journal of Applied Clinical Pediatrics
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the pathogenic effect of serum platelet derived growth factor(PDGF) in Henoch - Schonlein pur-pura nephritis(HSPN) and the influence of heparin. Methods The levels of serum PDGF were detected before and after heparin therapy by double antibody ELISA in the peripheral blood of patients. All patients were injected with heparin calcium[100 U/(kg?d)] for two to three weeks. Results The levels of serum PDGF(596.23 ? 199.43) ng/L in 30 HSPN cases before heparin therapy were significantly higher than those of the control group(259.76?69.58) ng/L (P
