Activation and Apoptosis of Peripheral Blood Lymphocytes in Children with Henoch - Schonlein Purpura and Effects of Triptolide on Them
- VernacularTitle:过敏性紫癜急性期患儿淋巴细胞活化、凋亡及雷公藤对其作用
- Author:
wei, GUO
;
si-guang, LU
;
feng-jun, GUAN
;
tong-qiang, LIU
- Publication Type:Journal Article
- Keywords:
henoch-schonlein purpura;
activation;
apoptosis;
triptolide;
peripheral blood lymphocytes
- From:Journal of Applied Clinical Pediatrics
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the activation and apoptosis of peripheral blood lymphocytes(PBLs) in children with Henoch-Schonlein purpura(HSP) and the effects of triptoIide(TP) on them. Methods The changes of activation and apoptosis were observed on cultured PBLs in children with HSP and healthy controls ,and the effects of TP were compared respectively. Expression of CD3, CD25 and apoptosis rate of PBLs were assayed with flow cytometry. Results The percentage of CD3+ CD25+ cell was significantly higher (P
