Changes of insulin like growth factor - 1 in blood and cerebrospinal fluid in children with viral encephalitis
- VernacularTitle:病毒性脑炎患儿血和脑脊液胰岛素样生长因子-1的变化
- Author:
yi gang, MAN
;
xiao xia, LIN
;
zhi-rong, SHU
;
zi-pu, LI
- Publication Type:Journal Article
- Keywords:
vtral;
encephahtis;
children;
insulin like growth fnctur - 1
- From:Journal of Applied Clinical Pediatrics
2004;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the changes of insulin- like growth factor- 1(IGF-1)in blood and cerebrospinal fluid (CSF) in children with viral encephalitis (VE).Methods The IGF-1 levels in blood and CSF were determined before treatment by ELISA in 25 children who admitted with VE, including 15 cases with severe VE and another 10 cases with mild VE, 10 children served as con-trols. Results Before treatment, the blood IGF-1 levels in VE group were significantly lower than those of controls, but the CSF IGF-1 levels were significantly higher than those of controls(P0.05), but the blood IGF-1 levels in serve VE group were significanfly lower than those of mild VE group and controls(P
